Multiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis

The type 1 insulin-like growth factor receptor (IGF-1R), activated by its ligands, protects several cell types from a variety of apoptotic injuries. The main signaling pathway for IGF-1R-mediated protection from apoptosis has been previously elucidated and rests on the activation of phosphatidylinos...

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Main Authors: Peruzzi, Francesca, Prisco, Marco, Dews, Michael, Salomoni, Paolo, Grassilli, Emanuela, Romano, Gaetano, Calabretta, Bruno, Baserga, Renato
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84713/
https://ncbi.nlm.nih.gov/pubmed/10490655
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