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ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response

The ATM gene is mutated in the syndrome of ataxia telangiectasia (AT), associated with neurologic dysfunction, growth abnormalities, and extreme radiosensitivity. Insulin-like growth factor-I receptor (IGF-IR) is a cell surface receptor with tyrosine kinase activity that can mediate mitogenesis, cel...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Peretz, Shani, Jensen, Ryan, Baserga, Renato, Glazer, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11172010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041416598
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