The BH3 Domain of Bcl-x(S) Is Required for Inhibition of the Antiapoptotic Function of Bcl-x(L)

bcl-x is a member of the bcl-2 family of genes. The major protein product, Bcl-x(L), is a 233-amino-acid protein which has antiapoptotic properties. In contrast, one of the alternatively spliced transcripts of the bcl-x gene codes for the protein Bcl-x(S), which lacks 63 amino acids present in Bcl-x...

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Bibliografiske detaljer
Main Authors: Chang, Brian S., Kelekar, Ameeta, Harris, Marian H., Harlan, John E., Fesik, Stephen W., Thompson, Craig B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84651/
https://ncbi.nlm.nih.gov/pubmed/10490606
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