The BH3 Domain of Bcl-x(S) Is Required for Inhibition of the Antiapoptotic Function of Bcl-x(L)

bcl-x is a member of the bcl-2 family of genes. The major protein product, Bcl-x(L), is a 233-amino-acid protein which has antiapoptotic properties. In contrast, one of the alternatively spliced transcripts of the bcl-x gene codes for the protein Bcl-x(S), which lacks 63 amino acids present in Bcl-x...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Chang, Brian S., Kelekar, Ameeta, Harris, Marian H., Harlan, John E., Fesik, Stephen W., Thompson, Craig B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6673
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