Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner

The association of Sm proteins with U small nuclear RNA (snRNA) requires the single-stranded Sm site (PuAU(4–6)GPu) but also is influenced by nonconserved flanking RNA structural elements. Here we demonstrate that a nonameric Sm site RNA oligonucleotide sufficed for sequence-specific assembly of a m...

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Auteurs principaux: Raker, Veronica A., Hartmuth, Klaus, Kastner, Berthold, Lührmann, Reinhard
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84625/
https://ncbi.nlm.nih.gov/pubmed/10490595
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