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Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner

The association of Sm proteins with U small nuclear RNA (snRNA) requires the single-stranded Sm site (PuAU(4–6)GPu) but also is influenced by nonconserved flanking RNA structural elements. Here we demonstrate that a nonameric Sm site RNA oligonucleotide sufficed for sequence-specific assembly of a m...

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Pubblicato in:Mol Cell Biol
Autori principali: Raker, Veronica A., Hartmuth, Klaus, Kastner, Berthold, Lührmann, Reinhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6554
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