The Ras Mutant D119N Is Both Dominant Negative and Activated
The introduction of mutation D119N (or its homolog) in the NKxD nucleotide binding motif of various Ras-like proteins produces constitutively activated or dominant-negative effects, depending on the system and assay. Here we show that Ras(D119N) has an inhibitory effect at a cell-specific concentrat...
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| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454576/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6297 |
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