The Ras Mutant D119N Is Both Dominant Negative and Activated

The introduction of mutation D119N (or its homolog) in the NKxD nucleotide binding motif of various Ras-like proteins produces constitutively activated or dominant-negative effects, depending on the system and assay. Here we show that Ras(D119N) has an inhibitory effect at a cell-specific concentrat...

Полное описание

Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Cool, Robbert H., Schmidt, Gudula, Lenzen, Christian U., Prinz, Heino, Vogt, Dorothee, Wittinghofer, Alfred
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1999
Предметы:	Cell Growth and Development
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454576/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6297
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!