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The Ras Mutant D119N Is Both Dominant Negative and Activated

The introduction of mutation D119N (or its homolog) in the NKxD nucleotide binding motif of various Ras-like proteins produces constitutively activated or dominant-negative effects, depending on the system and assay. Here we show that Ras(D119N) has an inhibitory effect at a cell-specific concentrat...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Cool, Robbert H., Schmidt, Gudula, Lenzen, Christian U., Prinz, Heino, Vogt, Dorothee, Wittinghofer, Alfred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6297
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