SMG-2 Is a Phosphorylated Protein Required for mRNA Surveillance in Caenorhabditis elegans and Related to Upf1p of Yeast
mRNAs that contain premature stop codons are selectively degraded in all eukaryotes tested, a phenomenon termed “nonsense-mediated mRNA decay” (NMD) or “mRNA surveillance.” NMD may function to eliminate aberrant mRNAs so that they are not translated, because such mRNAs might encode deleterious polyp...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1999
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.5943 |
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