SMG-2 Is a Phosphorylated Protein Required for mRNA Surveillance in Caenorhabditis elegans and Related to Upf1p of Yeast

mRNAs that contain premature stop codons are selectively degraded in all eukaryotes tested, a phenomenon termed “nonsense-mediated mRNA decay” (NMD) or “mRNA surveillance.” NMD may function to eliminate aberrant mRNAs so that they are not translated, because such mRNAs might encode deleterious polyp...

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Autors principals: Page, Michelle F., Carr, Brian, Anders, Kirk R., Grimson, Andrew, Anderson, Philip
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84455/
https://ncbi.nlm.nih.gov/pubmed/10454541
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