Active-Site Mutations in the Xrn1p Exoribonuclease of Saccharomyces cerevisiae Reveal a Specific Role in Meiosis

Xrn1p of Saccharomyces cerevisiae is a major cytoplasmic RNA turnover exonuclease which is evolutionarily conserved from yeasts to mammals. Deletion of the XRN1 gene causes pleiotropic phenotypes, which have been interpreted as indirect consequences of the RNA turnover defect. By sequence comparison...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Solinger, Jachen A., Pascolini, Donatella, Heyer, Wolf-Dietrich
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.5930
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