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Active-Site Mutations in the Xrn1p Exoribonuclease of Saccharomyces cerevisiae Reveal a Specific Role in Meiosis

Xrn1p of Saccharomyces cerevisiae is a major cytoplasmic RNA turnover exonuclease which is evolutionarily conserved from yeasts to mammals. Deletion of the XRN1 gene causes pleiotropic phenotypes, which have been interpreted as indirect consequences of the RNA turnover defect. By sequence comparison...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Solinger, Jachen A., Pascolini, Donatella, Heyer, Wolf-Dietrich
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.5930
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