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Cell Cycle Control of Cdc7p Kinase Activity through Regulation of Dbf4p Stability

In Saccharomyces cerevisiae, the heteromeric kinase complex Cdc7p-Dbf4p plays a pivotal role at replication origins in triggering the initiation of DNA replication during the S phase. We have assayed the kinase activity of endogenous levels of Cdc7p kinase by using a likely physiological target, Mcm...

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Bibliografiske detaljer
Main Authors: Oshiro, Guy, Owens, Julia C., Shellman, Yiqun, Sclafani, Robert A., Li, Joachim J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84289/
https://ncbi.nlm.nih.gov/pubmed/10373538
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