Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase

Cdc7p-Dbf4p is a conserved protein kinase required for the initiation of DNA replication. The Dbf4p regulatory subunit binds Cdc7p and is essential for Cdc7p kinase activation, however, the N-terminal third of Dbf4p is dispensable for its essential replication activities. Here, we define a short N-t...

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Bibliographic Details
Main Authors: Miller, Charles T., Gabrielse, Carrie, Chen, Ying-Chou, Weinreich, Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682205/
https://ncbi.nlm.nih.gov/pubmed/19478884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000498
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