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Tyrosine Phosphorylation of the Proto-Oncoprotein Raf-1 Is Regulated by Raf-1 Itself and the Phosphatase Cdc25A

There is a growing body of evidence demonstrating that Raf-1 is phosphorylated on tyrosines upon stimulation of a variety of receptors. Although detection of Raf-1 tyrosine phosphorylation has remained elusive, genetic analyses have demonstrated it to be important for Raf-1 activation. Here we repor...

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Detalhes bibliográficos
Main Authors: Xia, Kai, Lee, Robert S., Narsimhan, Radha P., Mukhopadhyay, Nishit K., Neel, Benjamin G., Roberts, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84280/
https://ncbi.nlm.nih.gov/pubmed/10373531
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