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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation.

The Raf family of serine/threonine protein kinases couple growth factor receptor stimulation to mitogen activated protein kinase activation, but their own regulation is poorly understood. Using phospho-specific antisera, we show that activated Raf-1 is phosphorylated on S338 and Y341. Expression of...

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Hlavní autoři: Mason, C S, Springer, C J, Cooper, R G, Superti-Furga, G, Marshall, C J, Marais, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171298/
https://ncbi.nlm.nih.gov/pubmed/10205168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.8.2137
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