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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation.
The Raf family of serine/threonine protein kinases couple growth factor receptor stimulation to mitogen activated protein kinase activation, but their own regulation is poorly understood. Using phospho-specific antisera, we show that activated Raf-1 is phosphorylated on S338 and Y341. Expression of...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171298/ https://ncbi.nlm.nih.gov/pubmed/10205168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.8.2137 |
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