p70(s6k) Integrates Phosphatidylinositol 3-Kinase and Rapamycin-Regulated Signals for E2F Regulation in T Lymphocytes

In T lymphocytes, the hematopoietic cytokine interleukin-2 (IL-2) uses phosphatidylinositol 3-kinase (PI 3-kinase)-induced signaling pathways to regulate E2F transcriptional activity, a critical cell cycle checkpoint. PI 3-kinase also regulates the activity of p70(s6k), the 40S ribosomal protein S6...

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Detalles Bibliográficos
Main Authors: Brennan, Paul, Babbage, J. W., Thomas, G., Cantrell, Doreen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Transcriptional Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84271/
https://ncbi.nlm.nih.gov/pubmed/10373522
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