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Phosphoinositide 3-kinase (PI3K) and the nutrient sensing mTOR (mammalian target of rapamycin) pathways control T cell migration

The established role for Phosphatidylinositol (3,4,5) triphosphate (PI(3,4,5)P(3)) signalling pathways is to regulate cell metabolism. More recently it has emerged that PI(3,4,5)P(3) signalling via mTOR and Foxo transcription factors also controls lymphocyte trafficking by determining the repertoire...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Finlay, David, Cantrell, Doreen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520021/
https://ncbi.nlm.nih.gov/pubmed/20146713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05134.x
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