Ras-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf

The full-length versions of the Ras-specific exchange factors Ras-GRF1 (GRF1) and Ras-GRF2 (GRF2), which are expressed in brain and a restricted number of other organs, possess an ionomycin-dependent activation of Erk mitogen-activated protein kinase activity in 293T cells (C. L. Farnsworth et al.,...

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Auteurs principaux: Anborgh, Pieter H., Qian, Xiaolan, Papageorge, Alex G., Vass, William C., DeClue, Jeffrey E., Lowy, Douglas R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Cell Growth and Development
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84259/
https://ncbi.nlm.nih.gov/pubmed/10373510
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