Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in Saccharomyces cerevisiae

A cause of aging in Saccharomyces cerevisiae is the accumulation of extrachromosomal ribosomal DNA circles (ERCs). Introduction of an ERC into young mother cells shortens life span and accelerates the onset of age-associated sterility. It is important to understand the process by which ERCs are gene...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Park, Peter U., Defossez, Pierre-Antoine, Guarente, Leonard
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3848
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