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Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in Saccharomyces cerevisiae

A cause of aging in Saccharomyces cerevisiae is the accumulation of extrachromosomal ribosomal DNA circles (ERCs). Introduction of an ERC into young mother cells shortens life span and accelerates the onset of age-associated sterility. It is important to understand the process by which ERCs are gene...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Park, Peter U., Defossez, Pierre-Antoine, Guarente, Leonard
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3848
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