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A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genetic loci, including the ribosomal DNA (rDNA). Silencing at telomeres (telomere position effect [TPE]) and the cryptic mating-type loci (HML and HMR) depends on the silent information regulator genes, SIR1, SIR2, SIR3, and SI...

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Detalles Bibliográficos
Main Authors: Smith, Jeffrey S., Caputo, Emerita, Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84112/
https://ncbi.nlm.nih.gov/pubmed/10082585
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