A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genetic loci, including the ribosomal DNA (rDNA). Silencing at telomeres (telomere position effect [TPE]) and the cryptic mating-type loci (HML and HMR) depends on the silent information regulator genes, SIR1, SIR2, SIR3, and SI...

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izdano v:	Mol Cell Biol
Principais autores:	Smith, Jeffrey S., Caputo, Emerita, Boeke, Jef D.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1999
Teme:	DNA Dynamics and Chromosome Structure
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3184
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