cdk1- and cdk2-Mediated Phosphorylation of MyoD Ser200 in Growing C2 Myoblasts: Role in Modulating MyoD Half-Life and Myogenic Activity

We have examined the role of protein phosphorylation in the modulation of the key muscle-specific transcription factor MyoD. We show that MyoD is highly phosphorylated in growing myoblasts and undergoes substantial dephosphorylation during differentiation. MyoD can be efficiently phosphorylated in v...

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Autores principales: Kitzmann, Magali, Vandromme, Marie, Schaeffer, Valerie, Carnac, Gilles, Labbé, Jean-Claude, Lamb, Ned, Fernandez, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC84110/
https://ncbi.nlm.nih.gov/pubmed/10082583
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