Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes

Brown adipose tissue (BAT) represents a promising agent to ameliorate obesity and other metabolic disorders. However, the abundance of BAT decreases with age and BAT paucity is a common feature of obese subjects. As brown adipocytes and myoblasts share a common Myf5 lineage origin, elucidating the m...

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Κύριοι συγγραφείς:	Chao Wang, Weiyi Liu, Yaohui Nie, Mulan Qaher, Hannah Elizabeth Horton, Feng Yue, Atsushi Asakura, Shihuan Kuang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2017-02-01
Σειρά:	EBioMedicine
Θέματα:	MyoD Myogenesis Repressor Adipogenesis Brown adipocytes CRISPR-Cas9
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2352396417300191
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