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MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD

Summary: Rhabdomyosarcoma (RMS) is the most common soft tissue cancer among children, characterized by a skeletal muscle lineage that is impaired from undergoing terminal differentiation. NF-κB is constitutively active in cancer cells and plays a critical role in cell survival. Although NF-κB is als...

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Principais autores: Alexander R. Oles, Peter Y. Yu, Abasi-ama Udeme, Sudarshana Sharma, Priya Londhe, Benjamin R. Pryce, Erin E. Talbert, Eric M. Hill, Carlos J. Miranda, Brian K. Kaspar, Michael A. Arnold, Jack Hyland, Cheryl A. London, Peter J. Houghton, David J. Wang, Ryan D. Roberts, Denis C. Guttridge
格式: Artigo
語言:Inglês
出版: Elsevier 2025-08-01
叢編:iScience
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2589004225014105
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