Concerted Activity of Tyrosine Phosphatase SHP-2 and Focal Adhesion Kinase in Regulation of Cell Motility

The coordinated interplay of substrate adhesion and deadhesion is necessary for cell motility. Using MCF-7 cells, we found that insulin-like growth factor I (IGF-I) induces the adhesion of MCF-7 to vitronectin and collagen in a dose- and time-dependent manner, suggesting that IGF-I triggers the acti...

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Hlavní autoři: Mañes, Santos, Mira, Emilia, Gómez-Mouton, Concepción, Zhao, Zhizuang Joe, Lacalle, Rosa Ana, Martínez-A., Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84106/
https://ncbi.nlm.nih.gov/pubmed/10082579
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