Hypersensitive Site 2 Specifies a Unique Function within the Human β-Globin Locus Control Region To Stimulate Globin Gene Transcription

The human β-globin locus control region (LCR) harbors both strong chromatin opening and enhancer activity when assayed in transgenic mice. To understand the contribution of individual DNase I hypersensitive sites (HS) to the function of the human β-globin LCR, we have mutated the core elements withi...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Bungert, Jörg, Tanimoto, Keiji, Patel, Sunil, Liu, Qinghui, Fear, Mark, Engel, James Douglas
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3062
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