Roles of the “Dispensable” Portions of RAG-1 and RAG-2 in V(D)J Recombination

V(D)J recombination is initiated by introduction of site-specific double-stranded DNA breaks by the RAG-1 and RAG-2 proteins. The broken DNA ends are then joined by the cellular double-strand break repair machinery. Previous work has shown that truncated (core) versions of the RAG proteins can catal...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Steen, S. B., Han, J.-O., Mundy, C., Oettinger, M. A., Roth, D. B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3010
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