Roles of the “Dispensable” Portions of RAG-1 and RAG-2 in V(D)J Recombination

V(D)J recombination is initiated by introduction of site-specific double-stranded DNA breaks by the RAG-1 and RAG-2 proteins. The broken DNA ends are then joined by the cellular double-strand break repair machinery. Previous work has shown that truncated (core) versions of the RAG proteins can catal...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Steen, S. B., Han, J.-O., Mundy, C., Oettinger, M. A., Roth, D. B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3010
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