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Expression of Mutated Paramecium Telomerase RNAs In Vivo Leads to Templating Errors That Resemble Those Made by Retroviral Reverse Transcriptase

Telomeric DNA consists of short, tandemly repeated sequences at the ends of chromosomes. Telomeric DNA in the ciliate Paramecium tetraurelia is synthesized by an error-prone telomerase with an RNA template specific for GGGGTT repeats. We have previously shown that misincorporation of TTP residues at...

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Publicat a:Mol Cell Biol
Autors principals: Ye, Amanda J., Haynes, W. John, Romero, Daniel P.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1999
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2887
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