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Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.

In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RN...

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Autores principales: Hostomsky, Z, Hughes, S H, Goff, S P, Le Grice, S F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC236660/
https://ncbi.nlm.nih.gov/pubmed/7509004
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