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Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.

In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RN...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Hostomsky, Z, Hughes, S H, Goff, S P, Le Grice, S F
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1970-1971.1994
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