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Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates.

Retroviruses are known to mutate at high rates. An important source of genetic variability is recombination taking place during reverse transcription of internal regions of the two genomic RNAs. We have designed an in vitro model system, involving genetic markers carried on two RNA templates, to all...

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Detalhes bibliográficos
Main Authors: Negroni, M, Ricchetti, M, Nouvel, P, Buc, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41453/
https://ncbi.nlm.nih.gov/pubmed/7542781
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