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Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates.

Retroviruses are known to mutate at high rates. An important source of genetic variability is recombination taking place during reverse transcription of internal regions of the two genomic RNAs. We have designed an in vitro model system, involving genetic markers carried on two RNA templates, to all...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Negroni, M, Ricchetti, M, Nouvel, P, Buc, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41453/
https://ncbi.nlm.nih.gov/pubmed/7542781
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