Synergism with Germ Line Transcription Factor Oct-4: Viral Oncoproteins Share the Ability To Mimic a Stem Cell-Specific Activity
Activation of transcription by Oct-4 from remote binding sites requires a cofactor that is restricted to embryonal stem cells. The adenovirus E1A protein can mimic the activity of this stem cell-specific factor and stimulates Oct-4 activity in differentiated cells. Here we characterize the Oct-4–E1A...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Cell Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
1999
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84056/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082529/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2635 |
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