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A Conserved Motif in Goosecoid Mediates Groucho-Dependent Repression in Drosophila Embryos

Surprisingly small peptide motifs can confer critical biological functions. One example is the WRPW tetrapeptide present in the Hairy family of transcriptional repressors, which mediates recruitment of the Groucho (Gro) corepressor to target promoters. We recently showed that Engrailed (En) is anoth...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jiménez, Gerardo, Verrijzer, C. Peter, Ish-Horowicz, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84001/
https://ncbi.nlm.nih.gov/pubmed/10022895
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