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Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless

The DNA-binding transcription factor Suppressor of Hairless [Su(H)] functions as an activator during Notch (N) pathway signaling, but can act as a repressor in the absence of signaling. Hairless (H), a novel Drosophila protein, binds to Su(H) and has been proposed to antagonize N signaling by inhibi...

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Autori principali: Barolo, Scott, Stone, Tammie, Bang, Anne G., Posakony, James W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC186408/
https://ncbi.nlm.nih.gov/pubmed/12154126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.987402
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