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A Conserved Motif in Goosecoid Mediates Groucho-Dependent Repression in Drosophila Embryos

Surprisingly small peptide motifs can confer critical biological functions. One example is the WRPW tetrapeptide present in the Hairy family of transcriptional repressors, which mediates recruitment of the Groucho (Gro) corepressor to target promoters. We recently showed that Engrailed (En) is anoth...

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Autors principals: Jiménez, Gerardo, Verrijzer, C. Peter, Ish-Horowicz, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84001/
https://ncbi.nlm.nih.gov/pubmed/10022895
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