Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless
The DNA-binding transcription factor Suppressor of Hairless [Su(H)] functions as an activator during Notch (N) pathway signaling, but can act as a repressor in the absence of signaling. Hairless (H), a novel Drosophila protein, binds to Su(H) and has been proposed to antagonize N signaling by inhibi...
Shranjeno v:
| izdano v: | Genes Dev |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2002
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.987402 |
| Oznake: |
Brez oznak, prvi označite!
|