Substrate Specificities of SR Proteins in Constitutive Splicing Are Determined by Their RNA Recognition Motifs and Composite Pre-mRNA Exonic Elements

We report striking differences in the substrate specificities of two human SR proteins, SF2/ASF and SC35, in constitutive splicing. β-Globin pre-mRNA (exons 1 and 2) is spliced indiscriminately with either SR protein. Human immunodeficiency virus tat pre-mRNA (exons 2 and 3) and immunoglobulin μ-cha...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Mayeda, Akila, Screaton, Gavin R., Chandler, Sharon D., Fu, Xiang-Dong, Krainer, Adrian R.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1999
Matèries:	Gene Expression
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.1853
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