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Activation of c-Jun N-Terminal Kinase 1 by UV Irradiation Is Inhibited by Wortmannin without Affecting c-jun Expression

Activation of c-Jun N-terminal kinases (JNKs)/stress-activated protein kinases is an early response of cells upon exposure to DNA-damaging agents. JNK-mediated phosphorylation of c-Jun is currently understood to stimulate the transactivating potency of AP-1 (e.g., c-Jun/c-Fos; c-Jun/ATF-2), thereby...

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Bibliografski detalji
Glavni autori: Fritz, G., Kaina, B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC83970/
https://ncbi.nlm.nih.gov/pubmed/10022864
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