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Interaction of Hematopoietic Progenitor Kinase 1 with Adapter Proteins Crk and CrkL Leads to Synergistic Activation of c-Jun N-Terminal Kinase

Hematopoietic progenitor kinase 1 (HPK1), a mammalian Ste20-related protein kinase, is an upstream activator of c-Jun N-terminal kinase (JNK). In order to further characterize the HPK1-mediated JNK signaling cascade, we searched for HPK1-interacting proteins that could regulate HPK1. We found that H...

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Autores principales: Ling, Pin, Yao, Zhengbin, Meyer, Christian F., Wang, Xuhong Sunny, Oehrl, Wolf, Feller, Stephan M., Tan, Tse-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC116064/
https://ncbi.nlm.nih.gov/pubmed/9891069
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