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A Premature Termination Codon Interferes with the Nuclear Function of an Exon Splicing Enhancer in an Open Reading Frame-Dependent Manner

Premature translation termination codon (PTC)-mediated effects on nuclear RNA processing have been shown to be associated with a number of human genetic diseases; however, how these PTCs mediate such effects in the nucleus is unclear. A PTC at nucleotide (nt) 2018 that lies adjacent to the 5′ elemen...

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Bibliografische gegevens
Hoofdauteurs: Gersappe, Anand, Pintel, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC83958/
https://ncbi.nlm.nih.gov/pubmed/10022852
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