Cyclosporin A Promotes Translational Silencing of Autocrine Interleukin-3 via Ribosome-Associated Deadenylation
Translation is regulated predominantly by an interplay between cis elements at the 3′ and 5′ ends of mRNAs and trans-acting proteins. Cyclosporin A (CsA), a calcineurin antagonist and blocker of interleukin-2 (IL-2) transcription in T cells, was found to inhibit translation of IL-3 mRNA in autocrine...
Sparad:
| I publikationen: | Mol Cell Biol |
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| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Taylor & Francis
1999
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.889 |
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