Regulation of Cyclin A-Cdk2 by SCF Component Skp1 and F-Box Protein Skp2
Cyclin A-Cdk2 complexes bind to Skp1 and Skp2 during S phase, but the function of Skp1 and Skp2 is unclear. Skp1, together with F-box proteins like Skp2, are part of ubiquitin-ligase E3 complexes that target many cell cycle regulators for ubiquitination-mediated proteolysis. In this study, we invest...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.635 |
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