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Cux/CDP Homeoprotein Is a Component of NF-μNR and Represses the Immunoglobulin Heavy Chain Intronic Enhancer by Antagonizing the Bright Transcription Activator

Nuclear matrix attachment regions (MARs) flanking the immunoglobulin heavy chain intronic enhancer (Eμ) are the targets of the negative regulator, NF-μNR, found in non-B and early pre-B cells. Expression library screening with NF-μNR binding sites yielded a cDNA clone encoding an alternatively splic...

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Published in:Mol Cell Biol
Main Authors: Wang, Zhiyong, Goldstein, Adrian, Zong, Rui-Ting, Lin, Danjun, Neufeld, Ellis J., Scheuermann, Richard H., Tucker, Philip W.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1999
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.284
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