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Transcriptional regulation of the human ALDH1A1 promoter by the oncogenic homeoprotein TLX1/HOX11

The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells, functions as a bifunctional transcriptional regulator, being capable of activation or repression depending on cell type and/or promoter context. However, the detailed mechan...

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Detalles Bibliográficos
Principais autores: Kim Rice, Mansour Heidari, Ross Taplin, Ursula Kees, Wayne Kenneth Greene
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2009-08-01
Series:Hematology Reports
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Acceso en liña:http://www.pagepress.org/journals/index.php/hr/article/view/202
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