Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress

Cancer cells reprogram cellular metabolism to maintain adequate nutrient pools to sustain proliferation. Moreover, autophagy is a regulated mechanism to break down dysfunctional cellular components and recycle cellular nutrients. However, the requirement for autophagy and the integration in cancer c...

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Publicado en:JCI Insight
Autores principales: Devenport, Samantha N., Singhal, Rashi, Radyk, Megan D., Taranto, Joseph G., Kerk, Samuel A., Chen, Brandon, Goyert, Joshua W., Jain, Chesta, Das, Nupur K., Oravecz-Wilson, Katherine, Zhang, Li, Greenson, Joel K., Chen, Y. Eugene, Soleimanpour, Scott A., Reddy, Pavan, Lyssiotis, Costas A., Shah, Yatrik M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328084/
https://ncbi.nlm.nih.gov/pubmed/34138755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138835
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