Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect

Acute graft-versus-host disease (GvHD) causes significant mortality in patients undergoing allogeneic hematopoietic cell transplantation. Immunosuppressive treatment for GvHD can impair the beneficial graft-versus-leukemia effect and facilitate malignancy relapse. Therefore, novel approaches that pr...

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Bibliographic Details
Published in:Haematologica
Main Authors: Haring, Eileen, Uhl, Franziska M., Andrieux, Geoffroy, Proietti, Michele, Bulashevska, Alla, Sauer, Barbara, Braun, Lukas M., de Vega Gomez, Enrique, Esser, Philipp R., Martin, Stefan F., Pfeifer, Dietmar, Follo, Marie, Schmitt-Graeff, Annette, Buescher, Joerg, Duyster, Justus, Grimbacher, Bodo, Boerries, Melanie, Pearce, Erika L., Zeiser, Robert, Apostolova, Petya
Format: Artigo
Language:Inglês
Published: Fondazione Ferrata Storti 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327708/
https://ncbi.nlm.nih.gov/pubmed/32675222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.242990
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