Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans

Acute graft-versus-host disease (GVHD) is a life-threatening complication after allogeneic hematopoietic cell transplantation (allo-HCT). Although currently used GVHD treatment regimens target the donor immune system, we explored here an approach that aims at protecting and regenerating Paneth cells...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Norona, Johana, Apostolova, Petya, Schmidt, Dominik, Ihlemann, Rebekka, Reischmann, Nadine, Taylor, Gregory, Köhler, Natalie, de Heer, Jocelyn, Heeg, Steffen, Andrieux, Geoffroy, Siranosian, Benjamin A., Schmitt-Graeff, Annette, Pfeifer, Dietmar, Catalano, Antonella, Frew, Ian J., Proietti, Michele, Grimbacher, Bodo, Bulashevska, Alla, Bhatt, Ami S., Brummer, Tilman, Clauditz, Till, Zabelina, Tatjana, Kroeger, Nicolaus, Blazar, Bruce R., Boerries, Melanie, Ayuk, Francis, Zeiser, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498363/
https://ncbi.nlm.nih.gov/pubmed/32542357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005957
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